Central Biobank Platform Sciensano
The Central Biobank Platform provides support to the different biobank modules of Sciensano. These Sciensano Biobank modules are available for internal as well as external scientists who want to do research involving human body material and require a biobanking facility. Samples can be registered, processed, stored and made available for scientific research, according to the applicable ethical and legal framework for biobanks. As a Central Biobank Platform, we can offer advice and operational support to these scientific projects in terms of biobanking activities. Requests for re-use of samples stored in the Sciensano Biobank will be evaluated based on the proposed research project. Samples will only be made available for proposed research projects of external researchers after approval of the medical manager of the involved Sciensano Biobank module and the Sciensano unit / department that was in charge of the primary study (i.e. the study collecting and using the samples for the first time).
The Human Embryonic and Induced Pluripotent Stem Cell Unit (HSCU) specializes in:
- Human embryonic stem cell (ESC) culture, maintenance and differentiation
- Generation of human induced pluripotent stem cells (iPSC) from somatic cells using cell reprogramming technologies
- Directed differentiation of pluripotent stem cells (ESC, iPSC) for the development of 2D and 3D cellular systems for modeling brain development and pathology.
The HSCU, in the context of collaborative projects or service contracts, offers:
Preclinical drug evaluation in human iPSC-based models of neurodegenerative diseases
- Generation of iPSC
- Development of iPSC-derived cellular systems
- Training in human stem cell culture principles, maintenance, and directed differentiation
- Training in the analysis of iPSC-derived cellular systems of human neurodegenerative diseases
- Consultancy for project development, protocol establishment, experimental design, troubleshooting
The main activity of TTL is the generation of genetically modified mice by using cutting-edge transgenic technologies with the aim to establish models for human diseases, as well as to perform preclinical drug evaluations in terms of high quality services or research collaborations to the national and international research community.
The Institut Pasteur de Lille-Biological Resources Center (IPL-CRB) is a technological platform of the Institut Pasteur de Lille created in 1998. Its missions are to collect, manage and enhance collections of biological resources, within the framework of projects concerning cardiovascular, metabolic, and neurodegenerative diseases.
The collection of Cyanobacteria maintains the collection Pasteur Cultures of Cyanobacteria (PCC), 800 monoclonal pure strains of Cyanobacteria.
The CNCM is an International Depositary Authority (IDA) under the Budapest Treaty (BT). The CNCM receives deposits of accepts bacteria, filamentous fungi, yeasts, bacteriophages, viruses, animal, and human cell lines, for national and international patent procedures or other purposes requiring high secrecy requirements.
The provision of biological material preserved at the CNCM is governed by the BT implementing regulations.
Development and harmonization of innovative methods for comprehensive analysis of food-borne toxigenic bacteria, i.e. Staphylococci, Bacillus cereus and Clostridium perfringens.
150,000 samples of human origin accompanied by demographic (sex, age), clinical (pathology), preanalytical and biological (basic measurements) data.
The Centre de Ressources Biologiques de l’Institut Pasteur, CRBIP, was created in 2001 as a transversal biobank infrastructure that includes microbial and human specimen collections of Institut Pasteur. The CRBIP receives, maintains, characterizes and supplies biological resources globally, in compliance with health and environmental safety standards and under applicable laws and regulations.
The Centre include 4 specific platforms:
-Collection of the Institut Pasteur (CIP)
-ICAReB-biobank : Integrated Collections for Adaptive Research in Biomedicine
-Collection Pasteur Culture of Cyanobacteria (PCC)
-National Collection of Cultures of Microorganisms
Access to biological resources distribution and deposits is only on remote basis:
-CRBIP catalogue of Microbial resources: https://catalogue-crbip.pasteur.fr/recherche_catalogue.xhtml. Contacts: cip@pasteur.fr (bacterial strains); collectionpcc@pasteur.fr (cyanobacterial strains); cvip@pasteur.fr (viral strains); cfip@pasteur.fr (fungal strains)
-Human biological resources: icareb-biobank@pasteur.fr
-Microbial strain and cell line deposits under the Budapest Treaty: cncm@pasteur.fr
Services: crbip-pmo@pasteur.fr
Current Prices (all prices are under revision)
These rates refer to 2023, please contact the team for a quote. Microbial resources:
-Bacteria and yeasts BSL1/2: 80 EUR
-Bacteria BSL3: 150 EUR -Strict anaerobic bacteria/Filamentous fungi: 100 EUR
-Cyanobacteria: 223 EUR
Human biological resources distribution: contact icareb-biobank@pasteur.fr
Microbial strains public deposits: free of charge
Microbial strain and cell line deposits under the Budapest Treaty (30 years deposits)
-Bacteria, Bacteriophages, Filamentous fungi, Yeasts: 701,27 EUR
-Virus propagated on cell lines: 1086,96 EUR
-Cell lines: 1448,27 EUR Services Microbial
-Preservation by freeze-drying: 162,60 EUR/strain
-Bacteria identification by MALDI-TOF MS: 74,50 EUR/strain
-Whole Genome Sequencing (Illumina) and taxonomic species classification: 391,40 EUR/strain
-Taxonomic species classification by MALDI-TOF MS + WGS: 460,50 EUR
-Bacterial genomic data assembly and analyses: 159,70 EUR/strain
-Sequence-based comparative genotyping: 319,40 EUR/strain
-Curation of data in existing cgMLST databases: 39,30 EUR
-Search of sequences of concern and genomic contextualization: 838,30 EUR
-Creation and/or curation of private genomic databases: inquire Human: see table below.