LIGAN MP – Genomics and Metabolic Diseases Platform

the LIGAN-PM platform is dedicated to next-generation sequencing and other state-of-the-art genomic technologies. Our sequencing and genotyping systems are primarily dedicated to precision medicine. However, the platform is opened to all applications related to genetics and genomics regardless of species. This platform includes several sequencing systems (MiSeq, NextSeq, NovaSeq), various robots for library preparation, a platform dedicated to genotyping and other state-of-the-art systems of genetics and genomics (such as NanoString).

Go@L is the genomic plateforme of the UAR (Unité d’Appui et de Recherche) PLBS (Plateformes Lilloises en Biologie & Santé) UMS2014 US41. This plateforme is composed of 2 laboratories, one team (GFS) at the CHRU and one team (TAG) at the Institute Pasteur de Lille. The plateforme is specialized in genomic and transcriptomic based on the use and development of molecular biology applications using high throughput sequencing technologies.
Our main applications are :
– Genomic : WGS, WES, amplicon-seq, Tn-seq, CGH-arrays.
– Transcriptomic : RNA-seq, sRNA-seq, bacterial RNA-seq, NGS-RACE, RNA-seq full-length, DGE, single-cell RNA-seq, spatial transcriptomic.
– Metagenomic : targeted bacterial 16S metagenomic

The platform has transverse and diversified expertise. Its scientific scope includes in particular :
-Omics data analysis (genomics, transcriptomics, proteomics, metagenomics, epigenetics, …)
-Sequence annotation
-Integrative biology
-Systems biology
-Image data analysis
-High content screening data analysis
-Phylogeny
-Structural bioinformatics

The Bioinformatics and Biostatistics Hub is a team of research engineers dedicated to bringing support in computational biology to Institut Pasteur’s research units and platforms. Expertise of the team is large and includes multi-OMICS data analysis, statistics, software and web interface development, among others. We interact with Pasteur scientists in many ways, such as collaborative projects, advice, training (on campus and outside)