This facility is part of the Institut Pasteur’s Center for Animal Resources and Research.

It produces mice harboring a human immune system (HIS mice) and provide expertise for the possible applications of this model.

HIS mice engrafted with human Hematopoietic stem cells (HSC) are advantageous in vivo models for long-term studies in the field of human immune cells biologyimmune-oncology and infectious disease. They constitute a small animal model in which to analyze potency and safety of new drugs modulating the immune system.